Sociedade Brasileira de Telecomunicações · desde 1983 secretaria@sbrt.org.br
← SBrT2020

Avaliação da Influência da Valinomicina via Bomba de Na⁺/K⁺ na Comunicação Molecular por Sinalização de Ca²⁺ em Astrócitos

Ittalo S. Silva, Kaique Rijkaard de Sousa Oliveira, Ricardo de S Farias, Carlos Danilo Regis
Sinalização de Ca²⁺AstrócitosValinomicinaBomba de Na⁺/K⁺

Resumo

Ca²⁺-Signaling-based Molecular Communication (MC) implies the propagation of Ca²⁺ ions through cells by diffusion, which is influenced by the presence of concentration regulative structures in the plasma membrane, as the Na⁺/K⁺ pump. The valinomycin is a substance that operates via Na⁺/K⁺ pump to facilitate the transportation of those molecules through the membrane. Thus, this paper implemented a MC system, in order to evaluate the influence of the valinomycin in the Ca²⁺-Signaling in astrocytes. The activity of the valiomycin led both the Ca²⁺ propagation in the cytosol and the gain of the system to increase 9.4% and about 7.85 dB, respectively.